5.0
(2 reviews)
£68.75 GBP
VAT of £11.46 GBP included
3.43 Points
Single Bottle (30 Servings)
SKU: UK13097
[ Details ]

This product qualifies for free or flat-rate delivery. Learn More

Benefits


  • Contains 800 mg of the well-researched ingredient Neuravena®
  • Contains 1,000 mg of the amino acid L-Tyrosine
  • The ingredients in Neuro Focus have been studied for their possible benefits in relation to the following:
    • Mental clarity, performance and drive
    • Concentration and alertness
    • Working memory
    • Sustained cognitive performance under stress
    • Supporting healthy levels of dopamine
    • Supporting cognitive flexibility

Product Classifications


Gluten-Free - The finished product contains no detectable gluten (<10ppm gluten)


No Detectable GMOs - The finished product contains no detectable genetically-modified organisms


Vegan - The product is made without ingredients produced by or derived from animals


Quality Standards - GMP Operations and Standardized Ingredients


Checked For: Heavy Metals, Microbiological Contaminants, Allergens, Residual Solvents, Potency, Purity and Identity

What Makes This Product Unique?


Some say our attention spans are shrinking, while others believe that the human brain is just evolving to function differently than it once did. Each of us has a different ability to concentrate, which can be somewhat influenced by contributing factors such as genetics, attention deficits, age, emotional flexibility and stress. The ever-evolving digital era we find ourselves in has forced many individuals to adapt and acquire the skill of splitting our concentration among multiple tasks simultaneously. Although technology has improved the speed at which we can communicate and work with each other, it has also enabled more distractions, leading some to take up the craft of multitasking to keep up with their day-to-day demands. Focus, or the ability to concentrate efforts on a task without interruption for a given time, is crucial to everyday functioning and personal safety. The distinctive Neuro Focus™ formula was developed with a unique blend of ingredients to offer support for working memory. (9)

Neuro Focus™ contains 800 mg of Neuravena® - an extract from a proprietary variety of wild green oat herb, Avena sativa L. - grouped with 1,000 mg of L-tyrosine. These ingredients might work together to promote the delivery of neurological properties to the brain that help to support mental drive and clarity while providing individuals with the added benefit of sustained cognitive performance. Breaking down the word Neuravena® (Neur, the Greek origin for the word ‘nerve,’ and Avena, an old-fashioned term for the word ‘oat’) hints at this ingredient’s function. Neuravena® contains various bioactive compounds, including antioxidants that have the potential to support cognitive performance and memory. (1) One study conducted on elderly volunteers with below-average cognitive performance required the volunteers to perform a cognitive task after consuming a single dose of Neuravena®.9 These volunteers showed a significantly greater amount of electrical brain activity within the frontal and temporal lobes of their brain, in comparison with the volunteers in the placebo group. (9) Thus, the study revealed that Neuravena® may support an increase in neurological brain activity that is linked to the areas of the brain that are associated with memory. (1, 9) Another study on the acute effects of Neuravena® demonstrated that those who were administered 800 mg of the supplement reported higher results on various cognitive tasks in comparison to the other test group who received 1600 mg of Neuravena®. (1) Overall, the study demonstrated that 800 mg or below of Neuravena® served as an optimal dose. (1)

L-tyrosine, the other main ingredient in Neuro Focus™, might work to promote cognitive performance, supporting the release of various neurotransmitters within the brain such as epinephrine, norepinephrine and dopamine. Each of these neurotransmitters carries messages between brain neurons and the nervous system and plays an important role in an individual’s alertness, adrenaline, wakefulness, retrieval of memory and motivation. A survey conducted on more than 2,000 business professionals revealed that 95% of those business professionals admitted to multitasking during meetings. A great number of those same individuals also reported that when multitasking, they had more difficulty retaining information and made more errors in their work. Supplementation of L-tyrosine has been shown to assist in the ability to switch between multiple cognitive concepts more easily and handle multiple cognitive thoughts or tasks simultaneously, skills that are paramount for multitasking more effectively.

Modern times call for modern measures, and Neuro Focus™ delivers a formula that may help support focus and cognitive energy while avoiding burnout. This vegan and gluten-free formula offers a brain supplement that provides nootropic support without relying on caffeine. Support your mental agility by adding a little extra nutrition into your everyday routine that might help sustain the cognitive performance you need to take on life’s daily challenges.

Key Ingredients


L-Tyrosine 1,000 mg

Tyrosine is a nonessential amino acid – meaning that it is naturally found in the body – synthesised from the essential amino acid phenylalanine. L-tyrosine is the precursor for the synthesis of catecholamines – hormones such as dopamine, norepinephrine and epinephrine, thyroid hormones and melanin. Dopamine, norepinephrine and epinephrine play roles in mental health, cognition, behaviour and stress response. Dopamine regulates your reward and pleasure centres and is also important for memory and motor skills. Additionally, low dopamine levels may be linked to reduced cognitive flexibility – our ability to switch between different mental sets, tasks or strategies. Norepinephrine and epinephrine are hormones responsible for the fight-or-flight response to stressful situations. Dietary sources of tyrosine include beans, nuts, seeds, dairy, meats, fish, eggs and some grains.

Neuravena 800 mg

Neuravena® is an extract from a proprietary variety of wild green oat herb, Avena sativa L., that provides natural support for mental fitness, concentration and cognitive performance in stressful situations.Key mechanisms of this wild green oat extract might include monamine oxidase B (MAOB) inhibition and phosphodiesterase 4 (PDE4) inhibition. MAOB is an enzyme that breaks down biogenic amines in the brain such as dopamine, phenylethylamine and benzylamine, and a lack of these biogenic amines is correlated with central nervous system dysfunctions. Neuravena® binds to, and consequently inhibits, MAOBs, therefore preventing the breakdown of amines, specifically dopamine. (9). This means that there will be a greater storage of dopamine available for the brain to release. (9). Another inhibition that Neuravena® shows is that of phosphodiesterase 4 (PDE4). (1) Phosphodiesterases (PDE) are also enzymes, although these enzymes break down cyclic nucleotides, and a lack of cyclic nucleotides is also correlated with central nervous system dysfunctions. PDE4 is a phosphodiesterase specific to cyclic adenosine monophosphate (cAMP) – a nucleotide known as a secondary “messenger” involved in many important biological processes. Neuravena® mediates PDE4-inhibition, consequently preventing the breakdown of cAMP, meaning there will be a greater storage of cAMP to maintain physiological brain functions.

FAQs


Are there any specific warnings associated with this supplement?

The amino acid Tyrosine is a precursor to thyroid hormone. Individuals with Graves’ disease or elevated thyroid hormone should consult with their health care provider before consuming this product.

Who should take this product?

This product is suited for those who want to supplement their diet to support mental energy, mental stamina and agility. This formula would also be suitable for individuals who have an occupation or a routine that requires a large proportion of their day to be spent online or on focused tasks.

Is Neuro Focus okay for women who are pregnant?

Individuals who are pregnant/breastfeeding should check with their healthcare providers prior to adding this supplement to their daily routine.

Can children take Neuro Focusformula?

No, this product is intended for those who are 18 years of age and older.

How long does it take for Neuro Focus to start working?

This supplement is expected to begin working within one hour of consumption but may differ slightly from person to person based on the speed at which metabolism occurs.

What are the directions to use this product?

Take 3 capsules in the morning (not with food) or 60 minutes prior to any activity which requires mental agility or stamina. It is recommended that you do not exceed more than 3 capsules per day.

Can I take more than one serving of Neuro Focusformula per day?

Do not exceed the recommended daily dose. Neuro Focus™ works within 60 minutes of oral consumption, and it is recommended that you find the most opportune time of the day to consume this product.

What other products would pair well with this product?

This formula would pair well with Isotonix OPC-3, Isotonix Essentials Turn UP*, Heart Health Omega lll, Thymenol, Isotonix Magnesium*, Isotonix Activated B-Complex and Isotonix ORAC*.
*Available on SHOPGLOBAL.COM

Could this supplement affect my sleep?

It is uncertain if Neuro Focus™ could have an effect on your sleep patterns. However, because this product contains ingredients that work to promote increased alertness and adrenaline, it is suggested that you do not consume too close to bedtime.

Science


  1. David O. Kennedy, Philippa A. Jackson, Joanne Forster, Julie Khan, Torsten Grothe, Tania Perrinjaquet-Moccetti & Crystal F. Haskell-Ramsay (2017) Acute effects of a wild green-oat (Avena sativa) extract on cognitive function in middle-aged adults: A double-blind, placebo-controlled, within-subjects trial, Nutritional Neuroscience, 20:2, 135-151, DOI: 10.1080/1028415X.2015.1101304
  2. Kennedy DO, Bonnländer B, Lang SC, Pischel I, Forster J, Khan J, Jackson PA, Wightman EL. Acute and Chronic Effects of Green Oat (Avena sativa) Extract on Cognitive Function and Mood during a Laboratory Stressor in Healthy Adults: A Randomised, Double-Blind, Placebo-Controlled Study in Healthy Humans. Nutrients. 2020 May 29; 12(6):1598. doi: 10.3390/nu12061598. PMID: 32485993; PMCID: PMC7352613.
  3. Ruchi Malik, Abhijeet Sangwan, Ruchika Saihgal, Dharam Paul Jindal and Poonam Piplani,“Towards Better Brain Management: Nootropics”, Current Medicinal Chemistry 2007; 14(2). https://doi.org/10.2174/092986707779313408
  4. Glisky EL. Changes in Cognitive Function in Human Aging. In: Riddle DR, editor. Brain Aging: Models, Methods, and Mechanisms. Boca Raton (FL): CRC Press/Taylor & Francis; 2007. Chapter 1. Available from: https://www.ncbi.nlm.nih.gov/books/NBK3885/
  5. Pasquinelli, Elena. (2018, September 11). Are digital devices altering our brains? Scientific American. Retrieved on February 14, 2020 from https://www. scientificamerican.com/article/are-digital-devices-altering-our-brains/
  6. https://hms.harvard.edu/news/screen-time-brain
  7. Hou, Haifeng, Shaowe Jia, Shu Hu, Rong Fan, Wen Sun, Taotao Sun, and Hong Zhang. “Reduced Striatal Dopamine Transporters in People with Internet Addiction Disorder.” Journal of Biomedicine & Biotechnology 2012 (2012): 854524. doi:10.1155/2012/854524.
  8. Berry AS, Shah VD, Baker SL, et al. Aging Affects Dopaminergic Neural Mechanisms of Cognitive Flexibility. J Neurosci. 2016; 36(50):12559-12569. doi:10.1523/JNEUROSCI.0626-16.2016
  9. Berry NM, Robinson MJ, Bryan J, Buckley JD, Murphy KJ, Howe PR. Acute effects of an Avena sativa herb extract on responses to the Stroop Colour-Word test. J Altern Complement Med. 2011 Jul; 17(7):635-7. doi: 10.1089/acm.2010.0450. PMID: 21711204.
  10. Colzato LS, Jongkees BJ, Sellaro R, Hommel B. Working memory reloaded: tyrosine repletes updating in the N-back task. Front Behav Neurosci. 2013; 7:200. Published 2013 Dec 16. doi:10.3389/fnbeh.2013.00200
  11. Dimpfel W, Storni C, Verbruggen M. Ingested oat herb extract (Avena sativa) changes EEG spectral frequencies in healthy subjects. J Altern Complement Med. 2011 May; 17(5):427-34. doi: 10.1089/acm.2010.0143. Epub 2011 May 12. PMID: 21563962.
  12. Banderet LE, Lieberman HR. Treatment with tyrosine, a neurotransmitter precursor, reduces environmental stress in humans. Brain Research Bulletin. 1989 Apr; 22(4):759-762. DOI: 10.1016/0361-9230(89)90096-8.
  13. Schellekens, C., Perrinjaquet-Moccetti, T., Wullschleger, C., & Heyne, A. (2009). An extract from wild green oat improves rat behaviour. Phytotherapy research, 23, 1371-1377. doi: 10.1002/ptr.2751
  14. Singh R, De S, Belkheir A. Avena sativa (Oat), a potential neutraceutical and therapeutic agent: an overview. Critical Reviews in Food Science and Nutrition. 2013 ;53(2):126-144. DOI: 10.1080/10408398.2010.526725.
  15. Steenbergen L, Sellaro R, Hommel B, Colzato LS. Tyrosine promotes cognitive flexibility: evidence from proactive vs. reactive control during task switching performance. Neuropsychologia. 2015 Mar; 69:50-5. doi: 10.1016/j.neuropsychologia.2015.01.022. Epub 2015 Jan 16. PMID: 25598314.
  16. Fernstrom JD, Fernstrom MH. Tyrosine, phenylalanine, and catecholamine synthesis and function in the brain. J Nutr. 2007 Jun; 137(6 Suppl 1):1539S-1547S; discussion 1548S. doi: 10.1093/jn/137.6.1539S. PMID: 17513421.
  17. Moccetti,T.Wullschleger,C.Schmidt,A.Aydogan,C.Kreuter,M. H. Bioactivity-based development of a wild green oat (Avena sativa L.) extract in support of mental health disorders. Zeitschrift für Phytotherapie 2006
  18. Goldstein D. S. (2010). Catecholamines 101. Clinical autonomic research: official journal of the Clinical Autonomic Research Society, 20(6), 331–352. https://doi.org/10.1007/s10286-010-0065-7
  19. Neri DF, Wiegmann D, Stanny RR, Shappell SA, McCardie A, McKay DL. The effects of tyrosine on cognitive performance during extended wakefulness. Aviat Space Environ Med. 1995 Apr; 66(4):313-9. PMID: 7794222.
  20. The State of Attention survey, Kelton Global March 7, 2018
  21. Hase A, Jung SE, aan het Rot M. Behavioral and cognitive effects of tyrosine intake in healthy human adults. Pharmacol Biochem Behav. 2015 Jun; 133:1-6. doi: 10.1016/j.pbb.2015.03.008. Epub 2015 Mar 20. PMID: 25797188.
  22. Lopez MJ, Mohiuddin SS. Biochemistry, Essential Amino Acids. [Updated 2021 Mar 26]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2021 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK557845/
  23. Institute of Medicine (US) Committee on Military Nutrition Research; Marriott BM, editor. Food Components to Enhance Performance: An Evaluation of Potential Performance-Enhancing Food Components for Operational Rations. Washington (DC): National Academies Press (US); 1994. 13, Effects of Nutrients on Neurotransmitter Release. Available from: https://www.ncbi.nlm.nih.gov/books/NBK209058/
  24. Buckholtz JW, Treadway MT, Cowan RL, et al. Dopaminergic network differences in human impulsivity. Science. 2010; 329(5991):532. doi:10.1126/science.1185778)
  25. Colzato LS, Jongkees BJ, Sellaro R, Hommel B. Working memory reloaded: tyrosine repletes updating in the N-back task. Front Behav Neurosci. 2013; 7:200. Published 2013 Dec 16. doi:10.3389/fnbeh.2013.00200
  26. Aquili L. The Role of Tryptophan and Tyrosine in Executive Function and Reward Processing. International Journal of Tryptophan Research. January 2020. doi:10.1177/1178646920964825)
  27. Jongkees, B. J., Hommel, B., Kühn, S., & Colzato, L. S. (2015). Effect of tyrosine supplementation on clinical and healthy populations under stress or cognitive demands: A review. Journal of Psychiatric Research, 70, 50-57. doi:10.1016/j.jpsychires.2015.08.014.
  28. Jongkees BJ. Baseline-dependent effect of dopamine's precursor L-tyrosine on working memory gating but not updating. Cogn Affect Behav Neurosci. 2020; 20(3):521-535. doi:10.3758/s13415-020-00783-8.
  29.  Sargis RM. An Overview of the Adrenal Glands: Beyond Fight or Flight. https://www.endocrineweb.com/endocrinology/overview-adrenal-glands
  30. Laverty R. Catecholamines: role in health and disease. Drugs. 1978 Nov; 16(5):418-40. doi: 10.2165/00003495-197816050-00003. PMID: 363400.
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  32. Cai, Z. (2014). Monoamine oxidase inhibitors: Promising therapeutic agents for Alzheimer's disease (Review). Molecular Medicine Reports, 9, 1533-1541. https://doi.org/10.3892/mmr.2014.2040
  33. Young SN. L-tyrosine to alleviate the effects of stress?. J Psychiatry Neurosci. 2007; 32(3):224.
  34. Keravis T, Lugnier C. Cyclic nucleotide phosphodiesterase (PDE) isozymes as targets of the intracellular signalling network: benefits of PDE inhibitors in various diseases and perspectives for future therapeutic developments. Br J Pharmacol. 2012; 165(5):1288-1305. doi:10.1111/j.1476-5381.2011.01729.x

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Displaying reviews  1 - 2 of 2

24/5/2022

by LindaN

Shop Consultant
REALLY WORKS!!

Really helps with FOCUS! Had to call the company to ask how it works so well! Seems like I'm not the only one! Thank you soooo much, MA, for such a QUALITY product! :)

Response from Customer Service:
25/5/2022

Dear Valued Customer,

Thank you for taking the time to share your thoughts on the Neuro Focus™! We are so happy to hear you are pleased with the product!

Thank you again!
The Product Information Team


18/3/2022

by JingW

Shop Consultant
Love Focus

Within 3 days of taking it , I felt the difference!! It is easier to focus on work in the whole day.

Response from Customer Service:
21/3/2022

Dear Valued Customer,

Thank you for taking the time to leave your thoughts on the Neuro Focus! We are happy to hear you are pleased with the product.

Thank you again!
The Market United Kingdom Team